Maraviroc

Generic name: maraviroc [ ma-RAV-i-rok ]
Brand name: Selzentry
Dosage forms: oral liquid (20 mg/mL), oral tablet (150 mg; 25 mg; 300 mg; 75 mg)
Drug class: Chemokine receptor antagonist

Medically reviewed by Drugs.com on Oct 28, 2024. Written by Cerner Multum.

What is maraviroc?

Maraviroc is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Maraviroc is used with other medications to treat CCR5-tropic HIV type 1, a virus that can cause acquired immunodeficiency syndrome (AIDS). Maraviroc is not a cure for HIV or AIDS.

Maraviroc is for use in adults and children who weigh at least 4.4 pounds (2 kilograms).

Maraviroc may also be used for purposes not listed in this medication guide.

Maraviroc side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Stop taking maraviroc and seek medical treatment at once if you have a serious drug reaction that can affect many parts of your body (especially your liver). Symptoms may include: itching or rash, fever, swollen glands, muscle or joint aches, severe weakness, unusual bruising, upper stomach pain, vomiting, dark urine, or jaundice (yellowing of the skin or eyes).

Call your doctor at once if you have a side effect such as:

• a light-headed feeling, like you might pass out; or

• chest pressure, tight feeling in your neck or jaw, sweating, pain spreading to your arm or shoulder.

Maraviroc affects your immune system, which may cause certain side effects (even weeks or months after you've taken maraviroc). Tell your doctor if you have:

• signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;

• trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or

• swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.

Common side effects of maraviroc may include:

• fever, cold symptoms, cough;

• indigestion, gas, bloating, nausea, vomiting, diarrhea, constipation;

• rash;

• dizziness; or

• (in newborns) abnormal blood tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

If you have severe kidney disease, you may not be able to take maraviroc if you use certain other medications. Tell your doctor about all other medications you use.

Stop taking this medicine and seek medical treatment at once if you have a serious drug reaction that can harm your liver. Symptoms may include: itching or rash, vomiting, upper stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).

Before taking this medicine

If you have severe or end-stage kidney disease, you may not be able to take maraviroc if you use certain medications, including some antibiotics or antifungal medications, some heart or blood pressure medicines, St. John's wort, and certain drugs to treat hepatitis or tuberculosis. Tell your doctor about all other medications you use.

Tell your doctor if you have ever had:

• kidney disease (or if you are on dialysis);

• liver disease, especially hepatitis B or C;

• heart disease; or

• low blood pressure.

Maraviroc affects your immune system and may possibly increase your risk of developing infections or cancer. Ask your doctor about this risk.

Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.

Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Maraviroc is not approved for a premature baby, or a child who weighs less than 4.4 pounds (2 kilograms).

How should I take maraviroc?

Before you are treated with maraviroc, your doctor may perform a blood test to make sure maraviroc is the right treatment for your type of HIV.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Maraviroc must be given in combination with other antiviral medications and it should not be used alone.

You may take maraviroc with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Tell your doctor if the child taking maraviroc has trouble swallowing the tablet whole.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Maraviroc doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.

Use all HIV medications as directed and read all medication guides you receive. Do not change your dose or stop using a medicine without your doctor's advice. Every person with HIV should remain under the care of a doctor.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Get your prescription refilled before you run out of medicine completely.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking maraviroc?

Do not take an herbal supplement containing St. John's wort.

Avoid driving or hazardous activity until you know how maraviroc will affect you. Your reactions could be impaired.

Using this medicine may not prevent your disease from spreading. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

What other drugs will affect maraviroc?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect maraviroc. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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